Solid-phase synthesis of tris-heteroleptic ruthenium(II) complexes and application to acetylcholinesterase inhibition.
نویسندگان
چکیده
A synthetic route with two consecutive coordination chemistry steps on a solid support affords tris-heteroleptic ruthenium(II) polypyridyl complexes with high purity and in good yields. As an application we report the identification of a nanomolar acetylcholinesterase inhibitor from a small ruthenium complex library synthesized on Lanterns.
منابع مشابه
Strategy for the stereochemical assignment of tris-heteroleptic Ru(II) complexes by NMR spectroscopy.
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ورودعنوان ژورنال:
- Inorganic chemistry
دوره 47 12 شماره
صفحات -
تاریخ انتشار 2008